Post-Transjugular Intrahepatic Portosystemic Shunt (TIPS) Hepatic Encephalopathy-A Review of the Past Decade’s Literature Focusing on Incidence, Risk Factors, and Prophylaxis
Friis KH, Thomsen KL, Laleman W, Montagnese S, Vilstrup H, Lauridsen MM J Clin Med Transjugular intrahepatic portosystemic shunt (TIPS) is an established treatment for portal hypertension and its’ complications in liver cirrhosis, yet the development of hepatic encephalopathy (HE) remains a significant concern. This review covers the reported incidence, risk factors, and management strategies […]
A PDZ scaffolding/CaM-mediated pathway in Cryptochrome signaling
Bellanda M, Damulewicz M, Zambelli B, Costanzi E, Gregoris F, Mammi S, Tosatto SCE, Costa R, Minervini G, Mazzotta GM Protein Sci Cryptochromes are cardinal constituents of the circadian clock, which orchestrates daily physiological rhythms in living organisms. A growing body of evidence points to their participation in pathways that have not traditionally been associated […]
Managing Circadian Disruption due to Hospitalization: A Pilot Randomized Controlled Trial of the CircadianCare Inpatient Management System
Mangini C, Zarantonello L, Formentin C, Giusti G, Domenie ED, Ruggerini D, Costa R, Skene DJ, Basso D, Battagliarin L, Di Bella A, Angeli P, Montagnese S J Biol Rhythms The objective of the present study was to test the effects of an inpatient management system (CircadianCare) aimed at limiting the negative impact of hospitalization […]
The Alarm Clock Against the Sun: Trends in Google Trends Search Activity Across the Transitions to and from Daylight Saving Time
Domenie ED, Zarantonello L, Mangini C, Formentin C, Giusti G, Ruggerini D, Cusumano P, Biscontin A, Costa R, Montagnese S J Circadian Rhythms The human circadian timing system depends on the light/dark cycle as its main cue to synchronize with the environment, and thus with solar time. However, human activities depend also on social time, […]
Minimal hepatic encephalopathy is associated with a higher risk of overt hepatic encephalopathy and poorer survival
Gairing SJ, Mangini C, Zarantonello L, Gioia S, Nielsen EJ, Danneberg S, Lok AS, Sultanik P, Galle PR, Labenz J, Thabut D, Marquardt JU, Bloom PP, Lauridsen MM, Montagnese S, Nardelli S, Labenz C J Intern Med Background and aims: Minimal hepatic encephalopathy (MHE) is a frequent complication in patients with liver cirrhosis. Its impact […]