Clinical value of asterixis in 374 well-characterised patients with cirrhosis and varying degree of hepatic encephalopathy
Formentin C, Zarantonello L, Mangini C, Angeli P, Merkel C, Montagnese S Digestive and Liver Disease Current guidelines for the diagnosis of hepatic encephalopathy (HE) include the clinical sign asterixis, which defines grade II overt HE in the absence of disorientation to time [ 1 ]. Asterixis has also been used as an outcome in clinical trials […]
Blood metabolomics undercovers inflammation-associated mitochondrial dysfunction as a potentian mechanism underlying ACLF
Moreau R, Clària J, Aguilar F, Fenaille F, Lozano JJ, Junot c, Colsch B, Caraceni P, Trebicka J, Pavesi M, Alessandria C, Nevens F, Saliba F, Welzel TM, Albillos A, Gustot T, Fernández J, Moreno C, Baldassarre M, Zaccherini G, Piano S, Montagnese S, Vargas V, Genescà J, Solà E, Bernal W, Butin H, Hautbergue […]
A meta-analysis of magnetic resonance spectroscopy in the diagnosis of hepatic encephalopathy
Zeng G, Penninkilampi R, Chaganti J, Montagnese S, Brew BJ, Danta M Neurology Objective Various imaging modalities have been used to explore pathogenic mechanisms and stratify the severity of hepatic encephalopathy (HE). The hypothesis of this meta-analysis was that there is a progressive identifiable derangement of imaging measures using magnetic resonance spectroscopy (MRS) related to the […]
Effect of Morning Light Glasses and Night Short-Wavelength Filter Glasses on Sleep-Wake Rhythmicity in Medical Inpatients
Formentin C, Carraro S, Turco M, Zarantonello L, Angeli P, Montagnese S Frontiers in physiology Sleep and circadian rhythm disorders are common amongst medical inpatients. They are caused by a mixture of factors, including noise, loss of habitual daily routines, and abnormal exposure to light, which tends to be insufficient in the day and too […]
Clinical, neuropsychological and neurophysiological indices and predictors of hepatic encephalopathy (HE)
Formentin C, Zarantonello L, Mangini C, Frigo A C, Montagnese S, Merkel C Liver International Background and Aims The occurrence of overt hepatic encephalopathy (HE) marks a significant progression in the natural history of liver disease. The aims of the present study were to: 1) describe a large cohort of patients with cirrhosis in terms […]